Endocrine Abstracts

IntroductionSome studies have shown low-density lipoprotein cholesterol (LDL) and triglyceride (TG) levels were significantly lower in high-Killip (III + IV) patients compared with low-Killip (I + II) patients and in those who died after acute myocardial infarction (AMI) compared with those who survived beyond 30 days, which they called lipid paradox. Elevated levels of LDL and triglycerides are important risk factors for cardiovascular disease, ...

BackgroundType 2 Diabetes Mellitus (T2DM) and Heart Failure (HF) are two directly related diseases associated with considerable morbimortality. The prevalence of HF in T2DM populations is up to 20%, 4 times higher than the general population. Additionally, health-related quality of life, hospitalizations for HF (HHF) and mortality risk are more common when both are present. Hence, HHF risk assessment in T2DM patients may lead to prompt preventive interve...

IntroductionCOVID-19 is an emerging disease caused by the new coronavirus (SARS-CoV-2) that has overburdened healthcare worldwide. In Portugal, schedule appointments were cancelled, postponed or changed to tele-consultation. The objective of the study is to assess the impact of the pandemic on the use of Emergency Department (ED) by diabetic patients.Material and methodsRetrospective monocentric study of the ...

8-year-old girl is referred to a Pediatric Endocrinologist for the appearance of thelarche, first noted at 6.5 years. She had a relevant clinical history of a neonatal meningitis, requiring prolonged hospitalization and the need for ventriculoperitoneal shunt. On physical examination, she had breast development and dark, coarse pubic hair compatible with Tanner stage 3. She weighed 32.3 kg (percentile – Pc- 75–90), her height was 128 cm (Pc 50) and her annual growth ...

IntroductionFollicular thyroid carcinoma (FTC) has metastasis in 10-15%; papillary thyroid carcinoma (PTC) rarely metastasizes. Bone metastasis are rare and can cause pain, fractures and spinal cord compression.Case-172 year-old male referred to the hospital with lower back pain. Imaging examination revealed lytic lumbar lesions. Thoracic-abdominal-pelvic-CT showed trachea compression by a multinodular right ...

IntroductionNon-classical congenital adrenal hyperplasia (NC-CAH) is a chronic disease characterized by excessive androgen production. Affected children may have their quality of life negatively affected by the awareness of a medical condition, symptoms of hyperandrogenism and the burden of daily medication administration. Pediatric Quality of Life Inventory 4.0 (PedsQL) is a validated tool to assess health-related QoL (HRQoL).Meth...

Introduction: Magnesium (Mg) is an essential mineral for human health. Chronic Mg2+ deficiency and low Mg2+ dietary intake have been associated with increased risk of T2DM. Despite the increased risk of T2DM associated with Mg2+ deficiency; T2DM is often accompanied by hypomagnesemia, especially in patients with poorly controlled glycemic profiles.Bariatric surgery remains the most effective long-term therapy for the management of patients wi...

Introduction: Despite the abundance of data addressing the influence of patient’s age on surgery-related complications, its impact on several cardiovascular risk factors following bariatric surgery has been overlooked.Methods: Retrospective unicentric study of 1728 obese patients who underwent bariatric surgery between January/2010 and June/2015. Patients were divided in three groups, according to their age at surgery: <40 (n = 751...